How "I3C" blocks Breast Cancer cells

This is URGENT, BREAKING NEWS.

A major research report regarding Breast Cancer has just hit my desk from the journal of Cancer Prevention Research.

Every woman in the world needs to read this vitally important piece of news. It is all about a very special natural compound I have been advocating for years and years called Indole-3-Carbinol.

As a woman, if you are not already taking this formula, read every word of this research study to find out why it is vital that you do.

And it is just as important for men too.

An article just published in the journal Cancer Prevention Research clarifies the role of Indole-3-Carbinol (I3C), a compound metabolized from broccoli and brussel sprouts, in preventing several types of cancer.

Here’s a summary of the report published June 29, 2010.

A Novel Mechanism of Indole-3-Carbinol Effects on Breast Carcinogenesis Involves Induction of Cdc25A Degradation
Authors: Yongsheng Wu, Xiaoling Feng, Yucui Jin, Zhaojia Wu, William Hankey, Carolyn Paisie, Lei Li, Fengjuan Liu, Sanford H. Barsky, Weiwei Zhang, Ramesh Ganju and Xianghong Zou

Researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) describe the results of experiments with three human breast cancer cell lines which determined that I3C destroys “Cdc25A”, a molecule essential for cell division and proliferation.

“Cdc25A is present at abnormally high levels in about half of breast cancer cases, and it is associated with a poor prognosis,” explained lead researcher Xianghong Zou, who is an assistant professor of pathology at the Ohio State University Medical Center and a member of the OSUCCC-James Molecular Carcinogenesis and Chemoprevention program.

Dr Zou added that “Cdc25A” is also increased in prostate, liver, esophagus, endometrial and colon cancer, in non-Hodgkin lymphoma, and in Alzheimer’s and other diseases.

“For this reason, a number of anti-Cdc25 agents have been identified, but they have not been successful for cancer prevention or treatment due to concerns about their safety or efficacy,” he noted.

In another experiment, Dr Zou’s team tested the effect of oral Indole-3 Carbinol (I3C) supplementation in mice implanted with breast cancer cells and found a 65 percent average reduction in tumor size.

(My bold emphasis. Did you catch that? A 65 percent reduction in tumor size! If a drug were to achieve a 65% reduction, big pharma would be claiming they’ve cured cancer! Dr G.)
Continue reading “How "I3C" blocks Breast Cancer cells”