How "I3C" blocks Breast Cancer cells


A major research report regarding Breast Cancer has just hit my desk from the journal of Cancer Prevention Research.

Every woman in the world needs to read this vitally important piece of news. It is all about a very special natural compound I have been advocating for years and years called Indole-3-Carbinol.

As a woman, if you are not already taking this formula, read every word of this research study to find out why it is vital that you do.

And it is just as important for men too.

An article just published in the journal Cancer Prevention Research clarifies the role of Indole-3-Carbinol (I3C), a compound metabolized from broccoli and brussel sprouts, in preventing several types of cancer.

Here’s a summary of the report published June 29, 2010.

A Novel Mechanism of Indole-3-Carbinol Effects on Breast Carcinogenesis Involves Induction of Cdc25A Degradation
Authors: Yongsheng Wu, Xiaoling Feng, Yucui Jin, Zhaojia Wu, William Hankey, Carolyn Paisie, Lei Li, Fengjuan Liu, Sanford H. Barsky, Weiwei Zhang, Ramesh Ganju and Xianghong Zou

Researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) describe the results of experiments with three human breast cancer cell lines which determined that I3C destroys “Cdc25A”, a molecule essential for cell division and proliferation.

“Cdc25A is present at abnormally high levels in about half of breast cancer cases, and it is associated with a poor prognosis,” explained lead researcher Xianghong Zou, who is an assistant professor of pathology at the Ohio State University Medical Center and a member of the OSUCCC-James Molecular Carcinogenesis and Chemoprevention program.

Dr Zou added that “Cdc25A” is also increased in prostate, liver, esophagus, endometrial and colon cancer, in non-Hodgkin lymphoma, and in Alzheimer’s and other diseases.

“For this reason, a number of anti-Cdc25 agents have been identified, but they have not been successful for cancer prevention or treatment due to concerns about their safety or efficacy,” he noted.

In another experiment, Dr Zou’s team tested the effect of oral Indole-3 Carbinol (I3C) supplementation in mice implanted with breast cancer cells and found a 65 percent average reduction in tumor size.

(My bold emphasis. Did you catch that? A 65 percent reduction in tumor size! If a drug were to achieve a 65% reduction, big pharma would be claiming they’ve cured cancer! Dr G.)
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18 Things You Need to Know About Vitamin D and Cancer

The number one question that seems to be on everyone’s mind that I get asked nearly every single day is:

“Will we ever find a cure for Cancer?”

Despite the billions spent on “breakthrough” drugs and invasive surgical procedures, modern medicine is still no closer to solving this cruel, baffling and epidemic disease than we were 39 years ago, in 1971, when President Nixon declared a “war on cancer”.

vitamin D and the SunWhat we in the world of Natural and Alternative Medicine have done however, is something the medical and pharmaceutical cartels haven’t even thought of attempting or achieving; figuring out a way to PREVENT cancer in the first place.

The discovery of Vitamin D-3 and its powerful means of short-circuiting Cancer is the greatest tool at everyone’s disposal – and it is why I am screaming from the rooftops for everyone to make it as essential as a breath of air to stay alive.

Recently I ran across 18 observations, comments and truths that everyone needs to know about Vitamin D-3 and fighting cancer.

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Top Ten Breast Cancer Prevention Tips

Photo: AP
Photo: AP

Earlier this week, the White House put up a giant pink ribbon over the front steps in recognition of Breast Cancer Awareness Month.

Follow these “Top Ten” vital tips to help prevent Breast Cancer from occurring in the first place.

This Health Alert is not just for women – men need to know this information too!


1. Get regular mammograms. It sounds obvious, but you’d be surprised how many women don’t.

Earlier this month, an Australian study found that women who get regular mammograms had a 4.7 percent risk of dying of breast cancer; women who weren’t screened had a 56 percent mortality rate. Some women “hate” mammograms, I don’t like them either, see Tip #3 below.

2. Find out whether you or women close to you have “dense breasts”.

What does this mean? It means the breast cells grow and multiply more rapidly, raising your risk. Plus dense breasts make it harder for a mammogram to “see” through the tissue and detect a tumor.

While dense breast tissue is more common in younger women who haven’t yet had children, it’s also hereditary and can affect any woman. I have a dear 43-year-old friend whose breast tumor failed to show up on three years’ worth of mammograms before her doctor finally ordered an MRI.

How to find out? Schedule a breast exam and ask your doctor. Also talk to the radiologist who’s administering your mammogram.

3. Ask your doctor to recommend other tests.

Surprise: Mammograms are only 16 to 40 percent accurate, studies show.

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